Prophylactic Effect of Antiretroviral Therapy on Hepatitis B Virus Infection
نویسندگان
چکیده
منابع مشابه
Prophylactic effect of antiretroviral therapy on hepatitis B virus infection.
BACKGROUND Hepatitis B virus (HBV) infection is common in individuals infected with human immunodeficiency virus, especially in men who have sex with men (MSM). Almost all currently used regimens of antiretroviral therapy (ART) contain lamivudine (LAM) or tenofovir disoproxil fumarate (TDF), both of which have significant anti-HBV activity. However, the prophylactic effect of ART on HBV infecti...
متن کاملPostexposure prophylactic effect of hepatitis B virus (HBV)-active antiretroviral therapy against HBV infection.
Retrospective study indicates that hepatitis B virus (HBV)-active nucleoside (nucleotide) analogues (NAs) used for antiretroviral therapy reduce the incidence of acute HBV infections in human immunodeficiency virus (HIV)-infected patients. Learning from HIV postexposure prophylaxis (PEP), we explored the possibility of using NAs in PEP following HBV exposure, if preexposure prophylaxis is feasi...
متن کاملProtective effect of hepatitis B virus-active antiretroviral therapy against primary hepatitis B virus infection.
OBJECTIVE Current guidelines advise to vaccinate every hepatitis B virus (HBV)-susceptible HIV patient against HBV until sufficient antibody titers have been reached. However, in this era of combination antiretroviral therapy (cART), acute HBV infection rarely occurs in patients who lack this immune protection. We analyzed whether HBV-active cART (lamivudine, emtricitabine, tenofovir) might wor...
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Background and Aims: Many studies have provided evidence for the role of hepatitis B and C viruses in the development of liver cancer. Although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with HBV and HCV. This study was performed to determine the frequency of HBV/HCV-coinfection in Mashhad, North-East of Iran. Mat...
متن کاملEffect of antiretroviral HIV therapy on hepatitis B virus replication and pathogenicity.
Coinfections with hepatitis B virus (HBV) and HIV are very frequent. Although HBV is a DNA virus, it replicates via reverse transcription like HIV. Structural similarities between the enzymatic pocket of the HBV DNA polymerase and HIV-1 reverse transcriptase are the basis that certain drugs inhibit both enzymes and thus the replication of both viruses. HBV components increase the pathogenic act...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2013
ISSN: 1537-6591,1058-4838
DOI: 10.1093/cid/cit145